Subfailure overstretch injury leads to reversible functional impairment and purinergic P2X7 receptor activation in intact vascular tissue

Vascular stretch injury is associated with blunt trauma, vascular surgical procedures, and harvest of human saphenous vein for use in vascular bypass grafting.A model of subfailure overstretch in rat abdominal aorta was developed to characterize surgical vascular Tongue Depressors stretch injury.Longitudinal stretch of rat aorta was characterized e

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Revealing the Antiperspirant Components of Floating Wheat and Their Mechanisms of Action through Metabolomics and Network Pharmacology

Floating wheat is a classical herbal with potential efficacy in the treatment of hyperhidrosis.Aiming at revealing the main components and potential mechanisms of floating wheat, a comprehensive and unique phytopharmacology profile study was carried out.First, common wheat was used as a control to look for chemical markers of floating wheat.In the

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